K-BIO® CF PRESERVATIVE is a combination of formaldehyde and chloromethylisothiazolone / methylisothiazolone
(ratio 3:1). It is high performance liquid biocide recommended for use in: aqueous coatings, polymer dispersions,
filler suspensions, pigment slurries, solutions and dispersions of adhesive and thickeners, concrete admixture,
detergents, cleaning agents, polishes, ceramic glazes and as a tank side additive for diluted metalworking fluids.
The two active groups complement each other in the spectrum of efficacy and also in the time required for the effect.
The efficacy of K-BIO® CF PRESERVATIVE extends to gram-negative and gram-positive bacteria, moulds and
yeasts.
Product Highlight:
Broad spectrum bactericide and fungicide
Provide headspace protection
Quick and long term protection
Cost effective
Typical Properties
Active Ingredient:
5-Chloro-2-methyl-4-isothiazolin-3-one
2-Methyl-4-isothiazolin-3-one
Formaldehyde
Total Active Ingredients: ~ 30 -35%
Chemical Structure
Formaldehyde
mixture of 5-chloro-2-methyl-2H-isothiazol-3-one
(CMIT) and 2-methyl-2H-isothiazol-3-one (MIT) (3:1)
Physical Form Colorless to very slight yellow liquid
pH at 25°C (10% in aqueous solution) 2.0~6.0
Odor Pungent
Initial Boiling Point 100oC (212oF)
Density at 200C 1.01-1.30 g/mL
Usable in pH-range: 4 – 9
Use at temperatures up to 40 °C
Solubility fully miscible into water and soluble
into alcohols and some polar
solvents
Antimicrobial Spectrum
Minimum inhibitory concentrations (MIC) were determined by serial dilution of K-BIO® CF PRESERVATIVE
are shown in the table. The MIC indicates the concentration at which growth of the test organism is
completely inhibited under laboratory condition.
Minimum Inhibitory
Fungi Concentration
(%)
Aspergillus niger 0.04
Chaetomium globosum 0.04
Penicillium funiculosum 0.01
Aureobasidium pullulans 0..1
Yeast
Candida albicans 0.04
Saccharomyces cerevisiae 0.02
Bacteria
Gram-Positive
Bacillus subtilis 0.04
Staphylococcus aureus 0.04
Gram-Negative
Enterobacter aerogenes 0.04
Escherichia coli 0.01
Proteus vulgaris 0.04
Pseudomonas aeruginosa 0.04
Pseudomonas fluorescens 0.04
Use Recommendation
The amount of K-BIO® CF PRESERVATIVE required to provide protection to a formulation depends on the
susceptibility and potential contamination sources of a product. Our experience suggests that a level of K-BIO® CF
PRESERVATIVE of 0.05 – 0.2% by weight in the final formulation will protect aqueous products. It is recommended
that various levels of K-BIO® CF PRESERVATIVE be tested in the product to determine appropriate use levels. To
arrange for microbiological testing of your product to determine optimum use levels, contact your CDI
representative.
crylic, acrylic, butadiene, PVA and % Wt/Wt
Emulsion paints …………………………………………………………………………………………………………….. 0.05 – 0.20
Resins and adhesives…………………………………………………………………………………………………….. 0.05 – 0.20
Dispersion…………………………………………. …………………………………………………………………………… 0.05 – 0.20
Water based Preparations……………………………………. ………………………………………………………… 0.05 – 0.20
Storage and Disposal
Store in tightly closed original containers, in a dry and well ventilated place, at temperatures between 0 °C and
40 °C.
Keep away from metals, oxidation or reducing agents.
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